The 13 genes are ABCC12, CFTR, CTAGE1, DAOA-AS1, EFHC2, FHL5, GRIK2, NAV3, SPO11, SYCP2, TAAR9, TPH2, and ZNF157. Among the 10 diseases, two are male-specific (male infertility and non-syndromic oligospermia), four affect males more than females (X-linked mental retardation, generalized epilepsy, Sezary syndrome, cutaneous T-cell lymphoma), three affect females more than males (chronic fatigue syndrome, panic disorder, and pseudoxanthoma elasticum), and one displays distinct disease characteristics between males and females (personality disorders). Here, SPO11 is linked to Pseudoxanthoma elasticum.