SLC6A3 and schizophrenia: This posit is supported by an imaging study which reported no change in DAT in patients with schizophrenia after 6 months of treatment with haloperidol,47 and another study that showed existing lower striatal DAT levels in patients with schizophrenia did not change after 4-week treatment with antipsychotic drugs.48 Thus, overall current data from rat studies suggests that antipsychotic drug treatment is not likely to be a major confound in our study.