Notably, two meta-analyses of neuroimaging measuring DAT concluded there were no significant changes in levels of DAT in the striatum of patients with schizophrenia.5,14 These findings agree with some postmortem brain studies using tissue homogenates that have reported no changes in DAT in the striatum from patients with schizophrenia.15,16. The gene discussed is SLC6A3; the disease is schizophrenia.