Intriguingly, the ERBB3 mRNA expression pattern in prostate tumors of different Gleason grade was very similar to that of LRIG1 (Fig. 8e; compare with Supplementary Fig. 13a) and, in fact, LRIG1 mRNA levels correlated with those of ERBB3 but not of other ERBB members (Fig. 8f). The gene discussed is ERBB3; the disease is prostate neoplasm.