ELP5 and neoplasm: In xenograft models, no differences were observed in tumor volume growth and tumor weight between vehicle-treated WT and ELP5−/− tumor-bearing groups, but gemcitabine-treated ELP5−/− tumor-bearing groups exhibited markedly increased tumor volume growth and tumor weight compared with those in gemcitabine-treated WT tumor-bearing groups (Fig. 2h–j, Supplementary Fig. 3e–g).