DHCR7-DT and lung carcinoma: To further test specificity of the MSN-AP (labelled with Cy-5) to bind human cancer exosomes, we added MSN-AP (final concentration of 40 μg per ml) to blood samples obtained from eight lung cancer patients after approval by the hospital ethics committee and measured the formation of MSN-AP-bound exosomes by using flow cytometry after the sample incubation/centrifugation process.