TXN2 and atrial fibrillation: Similarly, C90 and C93 on mitochondrial thioredoxin (Txn2), C48 on mitochondrial peroxiredoxin-5 (Prdx5) and C32 and C35 on thioredoxin (Txn) were oxidized under BCNU/AF treatment, consistent with AF-mediated inhibition of thioredoxin reductase31 (Supplementary Data 3).