Indeed, SLC2A1 (which was up-regulated in our RNA-seq analysis as shown in Fig S2A and B) and HK2 (which was not amongst the DEGs in Fig S2) were both found to be significantly up-regulated in qRT-PCR analysis of the mouse IKKαKO urethane-induced large lung adenomas (Fig 8A and B); and SLC2A1 was also found to be enhanced in the IKKαKD H1437 tumor xenografts (Fig S4A). Here, HK2 is linked to lung adenoma.