An in silico meta-analysis of IKKα expression profiles with Kaplan–Meier plotter performed on a cohort of LCs showed that higher expression of IKKα was linked with overall survival in all LC cases and all cases of adenocarcinoma, but not in lung SCC cases (Xiao et al, 2015). The gene discussed is CHUK; the disease is laryngotracheoesophageal cleft.