The results of interest were the following: malnutrition, overweight, obesity, glucose metabolism, insulin resistance, diabetes, cholesterol metabolism, disturbances in adiponectin, leptin, and ghrelin levels, linear growth deceleration and growth hormone deficiency, gynaecological symptoms, thyroid diseases, endocrine cancers, hypocalcaemia, parathyroid hormone and vitamin D deficiency. The gene discussed is ADIPOQ; the disease is obesity due to melanocortin 4 receptor deficiency.