The result showed that RC was significantly associated with TPO-abs (p < 0.001, OR = 5.130, 95%CI = 2.064–12.752), and the association remained significant after adjusting for gender, age, marriage status, education, antidepressants treatment, comorbidity of thyroid diseases, and thyroid function (serum levels of FT3, FT4 and TSH) (p = 0.003). The gene discussed is TPO; the disease is thyroiditis.