To support the decreased blood levels of IGF-1 during sepsis, sepsis patients, when compared to healthy control subjects, displayed significantly increased blood levels of growth hormone (GH) (Fig. 1h, 0.98 ± 0.1 vs. 0.49 ± 0.2 ng/mL, p < 0.05) which normally responds to decreased blood levels of IGF-1 [21]. The gene discussed is IGF1; the disease is Sepsis.