While infection of DCs (Lin- CD45+ Ly6G- CD11b+ MHCII+) early in the course of disease was less apparent than that of monocytes (CD11b+ Ly6C+), a role for DCs in early infection cannot be excluded: our assays may not have been sensitive enough to detect them, or infected DCs may have been located in tissues that were not sampled. The gene discussed is PTPRC; the disease is infection.