To investigate the role of CCR7-mediated cell migration in Chlamydia dissemination, CCR7-/- and C57BL/6 mice (controls) were PV infected with 1x106 IFU of Chlamydia. We chose to use a higher dose, since this dose allows for 100% infection of the GI tract by 7 dpi. Here, CCR7 is linked to infection.