When human adipose-derived MSC (ASC) were IP injected in the DSS-induced acute and chronic colitis mouse models, histopathological severity of colitis, weight loss, diarrhea, inflammation, and survival rates improved, and ASC were reported to decrease inflammatory cytokine levels and correlated with the induction of IL-10-secreting T regulatory cells [23]. The gene discussed is IL10; the disease is Chronic colitis.