EGFR and glioblastoma: Reportedly, the presence of the X-linked alpha-thalassemia mental retardation syndrome (ATRX), p53 inhibition, intact 1p/19q, epidermal growth factor receptor (EGFR) amplification, and histone deacetylase (HDAc) expression correlate with poor prognosis and outcomes in patients with GBM [8–12].