Among them, mutations that showed notable inclinations for specific subtypes were TP53 (most frequent in the CIN subtype), CDH1 (more frequent in the GS subtype), PIK3CA (EBV-positive), RHOA (GS), ARID1A (EBV-positive and GS) and APC (CIN). The gene discussed is CDH1; the disease is cervical squamous intraepithelial neoplasia.