For example, elevated GalNAc-T mRNA expression in melanoma cells appears to be a biomarker for aggressive melanoma [16], Han et al. confirmed that the MAGE family member A9 had significantly higher expression in laryngeal squamous cellcarcinoma and could be used as an independent prognostic factor in patients with laryngeal squamous cell cancer [17]. The gene discussed is IGKV1D-22; the disease is melanoma.