CD4 and breast cancer: The results showed that JAK1 expression levels had a significantly positive correlation with infiltrating levels of CD8+ T cells (r = 0.373, P = 1.60e-33), CD4+ T cells (r = 0.225, P = 1.83e-12), macrophages (r = 0.315, P = 4.32e-24), neutrophils (r = 0.296, P = 9.54e-21), and dendritic cells (r = 0.226, P = 1.86e-12) in breast cancer and no significant correlations with B cells (r = 0.099, P = 1.98e-03) (Figure 4A).