Using data from the TCGA database, the expression of Unigene56159 was obtained and 151 cases of valid data collected and a significant positive correlation was identified between Unigene56159 expression and expression levels of the tumor proliferation marker; PCNA (r=0.3034; P=0.0003) and invasion markers MMP-2 (r=0.3072; P=0.0001) and MMP-9 (r=0.2936; P=0.0012; Fig. 3A). The gene discussed is MMP2; the disease is neoplasm.