MKI67 and Bowen disease of the skin: The Ki67 antigen is a marker of cell proliferation10, 11 correlated with tumor growth and higher risk of metastasis.12, 13 The nuclear expression of Ki67 has been previously studied in cutaneous neoplasms and is evidenced in AK, Bowen's disease, basal cell carcinoma (BCC), and SCC.14, 15 To date, there are no studies describing the expression of Ki67 in SFC activity.