LGR5 and neoplasm: The expression of a subset of genes is associated with CSCs, including markers such as Lgr5, CD133, and CD44, as well as other genes involved in the acquisition of stemness traits in tumor cells, such as transcription factors Nanog, Stat‐3, and c‐Myc (Gong et al., 2015; Hadjimichael et al., 2015).