Both serum albumin and CRP levels are decreased in HCC patients compared with their levels in patients with other types of cancer because albumin and CRP production are decreased in HCC patients with chronic hepatitis or liver cirrhosis.23 Albumin and CRP were decreased most apparently in patients with a GPS of 2 who have the worst postoperative survival among patients with the three types of GPS, because the cut‐offs for both serum albumin and CRP levels are used in the calculation of GPS. This evidence concerns the gene CRP and hepatocellular carcinoma.