In the univariate analysis, statistically significant prognostic factors for poor disease‐free survival (DFS) rate included CRP level >0.20 mg/dL, albumin level <3.5 g/dL, AST level >35 IU/L, platelet count <14 × 104/mm3, ICGR15 level >15%, AFP level >10 ng/mL, Child‐Pugh grade B, liver damage grades B and C, number of tumors >1, tumor size >50 mm, liver cirrhosis, MVI, IM, low PNI, high CAR, high GPS, high NLR, low LMR and high PI. This evidence concerns the gene AFP and neoplasm.