The data showed the ccRCC patients with high expression of CENPE, KIF20A, KIF4A, MELK, NCAPG, NDC80, NUF2, TOP2A, TPX2 and UBE2C gene had worse overall survival (Figs. 6A, 6C–6K, p < 0.05). Here, MELK is linked to nonpapillary renal cell carcinoma.