The American heart/stroke association (AHA/ASA) recommends tissue plasminogen activator (tPA), antiplatelet (aspirin, clopidogrel), anticoagulants (heparin, warfarin), antihypertensive and lipid-lowering agents for the treatment if ischemic stroke whereas osmotherapy, neuromuscular relaxants, neuroprotection and neuro-restoration therapy, reperfusion therapy and calcium channel blockers for hemorrhagic stroke [12,13]. This evidence concerns the gene PLAT and Stroke.