Furthermore, the percentages of GFP neutrophil cells in lyz transgenic larvae were significantly increased in Cu2+-stressed larvae at 4 h post both with and without A. hydrophila (72 hpf) infection (Figures S2D,E), and A. hydrophila infection significantly down-regulated the percentage of the lyz-GFP-positive cells in both the control and the Cu2+-stressed larvae at 92 hpf (24 hpi) (Figures S2D,E). The gene discussed is LYZ; the disease is infection.