Tauopathies are a family of neurodegenerative disorders characterized by intra-neuronal fibrillary aggregates containing abnormally hyperphosphorylated isoforms of the microtubule-associated protein Tau (Spillantini and Goedert, 2013; Alavi Naini and Soussi-Yanicostas, 2015; Wang and Mandelkow, 2016). The gene discussed is MAPT; the disease is tauopathy.