In fact, during the acute phases of ADS MOG+ and ADS AQP4+ NMOSD, cytokines related to B-lymphocytes, Th17 CD4+ cells, and neutrophils have been recurrently found elevated in the CSF [8, 10, 13–15], while MS patients rather express Th1 cytokines and chemokines [13]. Here, MOG is linked to myeloid sarcoma.