Serum IgA can induce additional effector functions such as ADCC and powerful neutrophil effector functions, although limited literature describes such processes in bacterial infection (Figure 3).37 ADCC has been observed to occur using vaccine‐induced sIgA and serum IgA against various bacterial species including Salmonella enterica serotype Typhi.59 Interestingly, other structures such as neutrophil extracellular traps (NETs) may also be key to IgA/FcαRI role in bacterial infection. Here, CD79A is linked to bacterial infectious disease.