NR4A1 and metastatic malignant neoplasm in the lymph nodes: In the multivariate analysis, lymph node metastasis (hazard ratio, 2.528; 95% CI, 1.318–4.850; p = 0.005), lymphovascular invasion (hazard ratio, 2.037; 95% CI, 1.099–3.775; p = 0.024), negative hormone receptor status (hazard ratio, 2.002; 95% CI, 1.169–3.430; p = 0.011) and high CIN (hazard ratio, 1.813; 95% CI, 1.067–3.080; p = 0.028) were revealed as independent factors of poor prognosis (Table 4).