Variables including CD4 cell count, serum HIV viral load (VL), high-sensitivity C-reactive protein (hs-CRP) and, N-terminal pro-brain natriuretic peptide (NT-proBNP) levels, estimated duration of HIV infection and traditional cardiovascular disease risk factors were analyzed for potential association with TTE abnormalities using Chi squared and Fisher’s exact tests. This evidence concerns the gene CD4 and HIV infectious disease.