IL13RA2 and central nervous system cancer: Therefore, Meenakshi et al. generated “OR” logic-gated CAR-T cells that contained distinct CAR molecules targeting two glioma-restricted antigens including HER2 and IL13Rα2 (HER2-targeted scFv CD28ζ and IL13Rα2- targeted scFv-CD28ζ) [34].