IL6 and juvenile polyposis syndrome: As a result, numerous serological markers for PJI have been evaluated in the past, including interleukin 6 (IL-6) [5], serum soluble intercellular adhesion molecule-1 (sICAM-1) [6], toll-like receptor(TLRs) [7], lipopolysaccharide-binding protein (LBP) [8, 9], myeloid-related protein14 (MRP-14) [10], and soluble urokinase plasminogen activation receptor (su-PAR) [11].