Correlation analysis of the prognostic factors associated with malignancy-associated HLH showed that Fib and DIC (r = 0.446, p = 0.037), ferritin and PLT (r = 0.516, p = 0.014), ALT (r = 0.481, p = 0.023), albumin and PLT (r = 0.483, p = 0.023), AST and ALT (r = 0.687, p = 0.001), and pleural effusion and pneumonia (r = 0.399, p = 0.041) were correlated. This evidence concerns the gene ALB and Pleural effusion.