The SDC-1 mRNA and protein expression were significantly up-regulated in pc-SDC-1-transfected group, compared with that in pcDNA3.1-transfected group (p < 0.001, Fig. 1c-d), hinting efficient overexpression of SDC-1 in human colorectal carcinoma cell lines. Here, SDC1 is linked to colorectal carcinoma.