The mice had a heart phenotype similar to hypertrophic cardiomyopathy that was recapitulated in multiple instances, which reported defective myocyte function and development of cardiac hypertrophy and lethal cardiomyopathy [36, 52–57] in mice bearing an p.Arg403Gln Myh7 variant. The gene discussed is MYH7; the disease is hypertrophic cardiomyopathy.