PRDX1 and tropical spastic paraparesis: In addition, antibodies against two HTLV-1 viral products, Tax and Gag p24, have been reported to cross-react with host antigens, heterogeneous ribonucleoprotein A1 and peroxiredoxin-1, respectively, suggesting that molecular mimicry may also play a role in the pathogenesis of HAM/TSP [100, 101].