In addition, analysis of a total of 26 biomarkers candidates in blood and CSF of HTLV-1 infected individuals and HAM/TSP patients demonstrated that CXCL10, CXCL9 and neopterin in CSF were the most strongly correlated with rate of disease progression of HAM/TSP [115]. The gene discussed is CXCL9; the disease is tropical spastic paraparesis.