MAP1LC3A and early-onset autosomal dominant Alzheimer disease: Nicardipine, another anti-hypertensive agent, consistently had one of the highest levels of activity in suppressing the abnormal accumulation of GFP-LC3 vesicles in CbCln3∆ex7/8/∆ex7/8 cells (Table 1 and Table S2, this study, and in [13]), and it was reported to potentially have a preventative effect in Alzheimer’s disease through its effects on the cerebral vasculature [51].