Together with the gene variant-based CCAH and CAIS examples, above, and that the non-aromatizable androgen, dihydrotestosterone (DHT) faithfully replicates T-induced behavioral organization in both gestational T-exposed macaque models for PCOS [168], models #3 and #5 (Figure 1), it is AR- and not ER-mediated brain action that “organizes” primate behavior. The gene discussed is AR; the disease is polycystic ovary syndrome.