On the other hand, the expression profiles of DCL1 and Homeobox leucine-zipper protein (HD-Zip III), and of their cognate miRNAs, sly-miR162 and sly-miR166a/b respectively, did not differ significantly upon viral infection, indicating that their gene expression homeostasis was not altered by PVYC-to (Figure 3c, Table S1). This evidence concerns the gene CD302 and viral infectious disease.