In fact, seven of these TADs did not comprise any prognostic pan-cancer genes, and among the remaining nine, only two TADs showed lower prediction power than the prognostic pan-cancer genes that they comprised (chr7:54760000-58079999, a prognostic TAD in LGG, comprising the prognostic pan-cancer gene EGFR; and chr12:55679000-57720999, a prognostic TAD in GBM, comprising the prognostic pan-cancer gene DDIT3; see Section 4, Figure 4C,D, and Supplementary Figure S6). The gene discussed is DDIT3; the disease is cancer.