CDKN2A and cancer: Thus, chr9:21240000-24400999 and chr9:24431000-24564999, two of the perturbed prognostic TADs for LGG, showed a relatively high number of CNVs, with a peak at the location of the pan-cancer gene CDKN2A (see Figure 5B); in the region comprising the perturbed prognostic TAD for LGG chr1:8000000-10440999, the number of CNVs decreased towards the 3′ end (see Figure 5C); and for the remaining perturbed prognostic TAD for LGG, chr3:196040000-198159999, we observed a general increase in the number of CNVs (see Figure 5D).