CD274 and neoplasm: A close examination of the studies of Ke et al. [36] suggests that the effects of baicalein was more pronounced on membrane surface expression of PD-L1 assayed by flow cytometry, than determination of total cellular expression of PD-L1 by western blotting, suggesting that baicalein might affect distinct pools of PD-L1 targeted for differential control of immune escape versus regulation of anti-tumor immunity in the tumor microenvironment.