Recently, in our published study, we first screened changes in PD-L1 expression by dietary polyphenols using human HCT116 colon cancer cells treated for 48 h with increasing concentration (5, 20 and 50 μM) of resveratrol (Res), piceatannol (Pic), pterostilbene (PTS), trimethylstilbene (TriMRes) and myricetin. This evidence concerns the gene CD274 and colonic neoplasm.