Of note, we found that alcohol consumption (HR: 1.809, 95% CI: 1.130‐2.896, P = .014), advanced stages (HR: 2.302, 95% CI: 1.249‐4.242, P = .007), lymphatic metastasis (HR: 1.653, 95% CI: 1.062‐2.573, P = .026), and high P4HA1 expression (HR: 1.865, 95% CI: 1.249‐2.785, P = .002) were significantly associated with shorter RFS (Table 2). This evidence concerns the gene P4HA1 and Lymphatic Metastasis.