As shown in Fig 3H, full‐length caspase‐11 and caspase‐1, as well as processed caspase‐11 (p26), caspase‐1 (p20), and GSDMD (p30, a marker of cell pyroptosis), were elevated on day 7 in colon tissue of GPx8−/− mice with colitis compared with samples from WT mice (Fig 3H). Here, GPX8 is linked to colitis.