The frequency of BRAF mutation in CRC reported in literature is around 4.7%‐20%.31 BRAF mutation is suggested to be associated with some clinical features such as right‐sided location, poor differentiation, peritoneal metastasis.32 No association between BRAF mutation and tumor location or metastatic sites was found, but we found that BRAFV600E mutation was associated with right‐sided location. This evidence concerns the gene BRAF and neoplasm.