TLR4 and chronic kidney disease: Furthermore, DF was also capable to inhibit the expression of ICAM‐1, TLR4 and vWF content on cells exposed to uraemic sera in a significant manner, decreasing their expression to control levels (0.4 ± 0.1%, 0.4 ± 0.1% and 4.1 ± 0.2%, respectively, n = 6, P < .05 vs CKD for ICAM and P < .05 vs CKD for TLR4 and vWF) (Figure 3).