We reported previously that treatment with SGLT2 significantly changed the rates of achieving the target BP (to 130/80 mmHg measured at the office and to 125/75 mmHg in the morning measured at home) in patients with diabetic nephropathy from 26.9% and 25.3% to 34.6% and 34.3%, respectively (p < 0.05, each) [21]. The gene discussed is SLC5A2; the disease is diabetic kidney disease.