GSTM1 and Hyperglycemia: Another study in Japan was conducted with on individuals who demonstrated mild hyperglycemia (fasting plasma glucose 105-125 mg/dL (5.8 mmol/L–6.9 mmol/L) or hemoglobin (Hb)A1c 6.1%-7.1%); they were randomly assigned to 4 groups with different doses of ALA: the results showed reduced fasting and 2 h post-OGTT plasma glucose levels after 3 months [39], and both studies reported no adverse effects [40, 41].