IL1A and diabetes mellitus: The same pattern was seen after the application of pressure alone, with an increase in the median IL-1α concentration in the control group 36.0 (26.8-55.4) vs. 15.4 (12.4-31.5) (P < 0.01), the DM PNP- group 32.2 (11.4-76.3) vs. 8.6 (0.8-21.9) (P < 0.01), and the DM PNP+ group 37.2 (19.5-76.6) vs. 14.5 (6.0-36.1) (P < 0.01).