On the other hand, transactivation of the complexes IL-6/STAT3/lncTCF7 or IL-6/STAT3/Snail-Smad3/TGF-β1 promotes the invasion of HCCs developed in patients with hepatitis [24, 38, 61], especially the nonalcoholic type [15]. The gene discussed is STAT3; the disease is Hepatitis.