Several lnRNAs are described as being involved in HCC progression: HOTTIP, HOXA13, MALAT1 (metastasis-associated lung adenocarcinoma transcript 1), HOTAIR (HOX transcript antisense RNA), HULC (highly upregulated in liver cancer), MEG3 (also known as GTL2), ZFAS1, ZEB1-AS1, ZEB2-AS1, Linc00974, Linc00261, H19, DANCR, TCF7, Dreh, MVIH, HEIH, LET, ATB, ITGB1, antisense Igf2r (AIR), CCAL, uc002mb, and PVT-1 [28, 34–41]. The gene discussed is HOTAIR; the disease is hepatocellular carcinoma.