As ZFAS1 contains a site for miR-150, which targets ZEB1 (which regulates E-cadherin), MMP14, and MMP16, we can suppose that ZFAS1 might play an important role in the EMT of HCC cells via matrix metalloproteinases and the Wnt/β-catenin pathway [28]. This evidence concerns the gene ZEB1 and hepatocellular carcinoma.