Spearman rank correlation analysis based on the IHC results of GPC3 and PGC-1α staining from 50 LC patients further indicated a significant negative correlation between the expressions of GPC3 and PGC-1α (r = −0.357, p=0.011) (Figures 3(c) and 3(d)). Here, PPARGC1A is linked to laryngotracheoesophageal cleft.