In the present study, to verify the possible role of OR2T6 in breast cancer, we tested the mRNA and protein levels of OR2T6 in breast cancer tissues in vivo; elucidated its functional role in breast cancer cell proliferation, invasion, and migration in vitro; and clarified its possible involvement in the regulation of the epithelial-mesenchymal transition (EMT) and the mitogen-activated protein kinase/extracellular regulated protein kinases (MAPK/ERK) pathway. The gene discussed is WNK2; the disease is breast carcinoma.